RESEARCH AREAS
The Subramanian lab works in the fields of innate immunity and systems immunology.View→
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at the Institute for Systems Biology
The Subramanian Lab
We study the mechanistic basis of innate
immunity and its impact on host defense and immune disease.
Affiliations
Dr. Naeha Subramanian holds affiliate appointments in the Department of Immunology and the Department of Global Health at the University of Washington. She takes graduate students from the Immunology and Pathobiology PhD programs.
Latest News
Dr. Naeha Subramanian Promoted to Associate Professor
Dr. Naeha Subramanian – an expert in immunology, innate immunity, and host-pathogen interactions, and head of ISB’s Subramanian Lab – has been promoted to Associate Professor. “I am honored with this promotion and excited about the incredible research being conducted in my lab. It is a pleasure and privilege to tackle exciting questions everyday,” she said.
Small, Persistent Increase in the Expression of NOD1 May Promote Cancer Risk
ISB researchers have found that a small, persistent increase in the expression of NOD1 could be responsible for higher cancer risks. The research team found that a slight 1.5-fold uptick in NOD1 expression can activate the protein and downstream signaling pathways in a manner similar to vast (30- to 200-fold) overexpression.
Inside the intense world of COVID-19 science, and unexpected findings from Seattle researchers
GeekWire published a story spotlighting ISB’s COVID-19 research. Reporter Lisa Stiffler spoke with ISB President Dr. Jim Heath about the breakneck pace ISB and all of our collaborative partners are working at to tease out COVID’s biological secrets to advance the understanding and treatment of the novel coronavirus.
How Salmonella Co-Opts the Host Immune System to Conceal Itself
While scientists have long studied bacterial infections, less attention has been paid to how the host immune response affects bacterial gene expression in the body. In a just-published paper in PNAS, ISB researchers detailed how the bacterium Salmonella conceals itself from the host immune system.
Dr. Subramanian Presents at Cytokines 2020
ISB Assistant Professor Dr. Naeha Subramanian presented at the virtual meeting, Cytokines 2020, on November 1-4. Talk are available on demand for the registrants until November 18.
COVID-19 Immune Response Study Could Lead to More Effective Treatments
Findings from the ISB-Swedish COVID-19 Immune Response Study suggest that treatments aimed at arresting the infection at the stage of moderate severity may be most effective. The team studied 139 patients and found that mild COVID-19 is very distinct from the moderate or severe forms of disease, which appear surprisingly similar.