Publications

Rommereim, L. M., Akhade, A. S., Dutta, B., Hutcheon, C., Lounsbury, N. W., Rostomily, C. C., Savan, R., Fraser, I. D. C., Germain, R. N., & Subramanian, N. (2020). A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses. Science Signaling, 13(661). https://doi.org/10.1126/scisignal.aba3244 Cite Download
Akhade, A. S., Atif, S. M., Lakshmi, B. S., Dikshit, N., Hughes, K. T., Qadri, A., & Subramanian, N. (2020). Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.2002747117 Cite Download
Su, Y., Chen, D., Yuan, D., Lausted, C., Choi, J., Dai, C. L., Voillet, V., Duvvuri, V. R., Scherler, K., Troisch, P., Baloni, P., Qin, G., Smith, B., Kornilov, S. A., Rostomily, C., Xu, A., Li, J., Dong, S., Rothchild, A., … Heath, J. R. (2020). Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19. Cell, S0092867420314446. https://doi.org/10.1016/j.cell.2020.10.037 Cite Download
Idso, M. N., Akhade, A. S., Arrieta-Ortiz, M. L., Lai, B. T., Srinivas, V., Hopkins, J. P., Gomes, A. O., Subramanian, N., Baliga, N., & Heath, J. R. (2020). Antibody-recruiting protein-catalyzed capture agents to combat antibiotic-resistant bacteria. Chemical Science, 11(11), 3054–3067. https://doi.org/10.1039/C9SC04842A Cite Download Download
Hampton, H., Hutcheon, C., & Subramanian, N. (2016). NAGging Hexokinase PEPs up NLRP3. Cell Host & Microbe, 20(2), 130–132. https://doi.org/10.1016/j.chom.2016.07.017 Cite Download
Rommereim, L. M., & Subramanian, N. (2015). AIMing 2 Curtail Cancer. Cell, 162, 18–20. https://doi.org/10.1016/j.cell.2015.06.041 Cite Download
Subramanian, N., Torabi-Parizi, P., Gottschalk, R. A., Germain, R. N., & Dutta, B. (2015). Network representations of immune system complexity. Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 7(1), 13–38. Cite Download
Hutcheon, C., Paulvannan, D., & Subramanian, N. (2015). Cyoplasmic sensing in innate immunity. In Encyclopedia of Cell Biology: Vol. Vol.3 (p. Pages 710-726). https://www.elsevier.com/books/encyclopedia-of-cell-biology/bradshaw/978-0-12-394447-4 Cite Download
Subramanian, N., Natarajan, K., Clatworthy, M. R., Wang, Z., & Germain, R. N. (2013). The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell, 153, 348–361. https://doi.org/10.1016/j.cell.2013.02.054 Cite Download
Lee, G.-S., Subramanian, N., Kim, A. I., Aksentijevich, I., Goldbach-Mansky, R., Sacks, D. B., Germain, R. N., Kastner, D. L., & Chae, J. J. (2012). The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature, 492, 123–127. https://doi.org/10.1038/nature11588 Cite Download
Kastenmüller, W., Torabi-Parizi, P., Subramanian, N., Lämmermann, T., & Germain, R. N. (2012). A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread. Cell, 150, 1235–1248. https://doi.org/10.1016/j.cell.2012.07.021 Cite Download
Ombrello, M. J., Remmers, E. F., Sun, G., Freeman, A. F., Datta, S., Torabi-Parizi, P., Subramanian, N., Bunney, T. D., Baxendale, R. W., Martins, M. S., Romberg, N., Komarow, H., Aksentijevich, I., Kim, H. S., Ho, J., Cruse, G., Jung, M.-Y., Gilfillan, A. M., Metcalfe, D. D., … Milner, J. D. (2012). Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions. N Engl J Med, 366, 330–338. https://doi.org/10.1056/NEJMoa1102140 Cite Download
Kastenmüller, W., Gasteiger, G., Subramanian, N., Sparwasser, T., Busch, D. H., Belkaid, Y., Drexler, I., & Germain, R. N. (2011). Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction. J Immunol, 187, 3186–3197. https://doi.org/10.4049/jimmunol.1101649 Cite Download
Subramanian, N., & Qadri, A. (2006). Lysophospholipid sensing triggers secretion of flagellin from pathogenic salmonella. Nat Immunol, 7, 583–589. https://doi.org/10.1038/ni1336 Cite Download