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Drs. Naeha Subramanian, Leah Rommereim Gilmore, and Ajay Suresh Akhade

Small, Persistent Increase in the Expression of NOD1 May Promote Cancer Risk

ISB researchers have found that a small, persistent increase in the expression of NOD1 could be responsible for higher cancer risks. The research team found that a slight 1.5-fold uptick in NOD1 expression can activate the protein and downstream signaling pathways in a manner similar to vast (30- to 200-fold) overexpression.